March 12, 2025
Global Brain has invested in Twelve Benefit Corporation, a company producing low carbon synthetic fuel and chemicals

Global Brain has invested in Twelve Benefit Corporation (Twelve), a company producing low carbon synthetic fuel (e-fuel) and chemicals, through its TOKYU-CNST GB Innovation Fund L.P. (TCIF).
Twelve is the carbon transformation company, a startup that uses CO₂ electrolysis as its core technology to produce synthetic fuels from carbon dioxide, water, and renewable energy to produce e-fuels and chemicals. In industries where electrification is challenging, such as aviation, maritime, and construction, the demand for low-carbon fuels is increasing. Compared to the current mainstream synthetic fuel production method, which relies on biomass as a feedstock, the e-fuel approach offers advantages in terms of raw material availability and greater CO₂ reduction potential, making it a promising future production method.
As one of the pioneering startups in the e-fuel space, Twelve is currently constructing its first commercial demonstration scale plant in the State of Washington, US. The sustainable aviation fuel (SAF) produced at this facility is already under offtake agreements with major airlines such as Alaska Airlines and International Airlines Group (IAG). Furthermore, Twelve’s synthetic fuel production process can be applied to a diverse range of products, including marine fuels, diesel, and naphtha, the latter being a feedstock for basic chemicals. Each of these products is garnering significant market interest.
Global Brain has decided to invest in Twelve based on our high regard for its strong research and development capabilities, its exceptional execution ability, its outstanding management team, and the significant market potential of synthetic fuels. Global Brain will contribute to the growth of Twelve in cooperation with TOKYU CONSTRUCTION CO., LTD.
About Twelve
- Location
- California, US
- CEO
- Nicholas Flanders
- Founded
- 2015
- URL
- https://www.twelve.co/
About TCIF
- Name
- TOKYU-CNST GB Innovation Fund L.P.
- General Partner
- Global Brain Corporation
- Fund Size
- JPY 5 billion
- Fund Term
- 10 years
About Global Brain
- Location
- Tokyo, Japan
- Representative
- Yasuhiko Yurimoto
- Founded
- January 1998
- URL
- https://globalbrains.com